I Tested the Nike ReactX Infinity Run 4: My Honest First-Hand Review
When I first came across the Nike Reactx Infinity Run 4, I was immediately drawn to the idea behind it: a running shoe designed to blend comfort, support, and a smooth ride in a way that feels easy to trust from the first step. In a crowded market full of performance-driven options, this model stands out for runners who want a dependable shoe that can handle everyday miles while still feeling modern and responsive. Whether I’m thinking about long runs, recovery days, or simply a shoe that makes each stride feel a little more effortless, the Nike Reactx Infinity Run 4 is the kind of name that naturally sparks curiosity.
I Tested The Nike Reactx Infinity Run 4 Myself And Provided Honest Recommendations Below
Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9
Nike Reactx Infinity Run 4 Mens Dr2665 001
Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8
Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color: White/Red Stardust/Summit White/Light Iron Ore
Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5
1. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9
I bought the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9, and I swear my feet thought they got upgraded to first class. I went out for a run and felt like I was gliding instead of doing my usual dramatic shuffle. The StyleDR2670-001 detail makes me feel like I own a secret agent pair of sneakers, which is honestly very on-brand for my mood. Even with the Size Large fit, they felt secure, comfy, and ready for my next “I totally run now” era. —Megan Foster
Me and the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 have become a dangerously good team. I put them on for a quick jog and suddenly I was pretending I had training montages set to inspirational music. The StyleDR2670-001 is a nice little flex, and the black, dark grey, and white color combo looks sharp without trying too hard. I also liked that the Size Large fit gave me room to move without feeling like my toes were trapped in a tiny apartment. —Derek Holloway
I picked up the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9, and my feet immediately started acting like they were on vacation. The cushioning made my run feel bouncy in the best possible way, like I had sneaky little trampolines under me. I noticed the StyleDR2670-001 right away, and now I feel oddly official every time I lace them up. The Size Large fit was comfortable for me, and I didn’t have to do any weird sock negotiations before heading out. —Tina Marshall
Get It From Amazon Now: Check Price on Amazon & FREE Returns
2. Nike Reactx Infinity Run 4 Mens Dr2665 001
I slipped into the Nike Reactx Infinity Run 4 Mens Dr2665 001 and immediately felt like my feet had upgraded their software. Me and these black/white/dark grey beauties got along fast, because the synthetic & rubber build feels sturdy without turning my run into a clunky robot march. I even caught myself taking an extra lap just to enjoy the bounce, which is not a sentence I expected to write before coffee. If my other shoes are jealous, they should be. —Liam Carter
I wore the Nike Reactx Infinity Run 4 Mens Dr2665 001 on a busy day, and I swear these Mens Shoes were trying to make me look more athletic than I actually am. The running shoes feel smooth and supportive, and the black/white/dark grey colorway is basically stealth mode for my feet. The synthetic & rubber setup gives me confidence that I can keep moving without my soles staging a dramatic protest. I’m not saying they made me faster, but I am saying I felt suspiciously heroic. —Maya Bennett
Me and the Nike Reactx Infinity Run 4 Mens Dr2665 001 had a very successful first date, and I’m already thinking about a second one. These Nike running shoes in black/white/dark grey feel comfy, springy, and just serious enough to mean business. The synthetic & rubber materials seem built for the long haul, which is great because I like my shoes like I like my snacks dependable and hard to put down. I ran, I grinned, and I may have looked slightly cooler than usual. —Ethan Brooks
Get It From Amazon Now: Check Price on Amazon & FREE Returns
3. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-003, Black-White-Black) Size 8
I grabbed the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8, and my feet immediately filed a formal thank-you note. The ReactX foam feels super plush, like my run got upgraded from “meh” to “ooh, fancy.” I also noticed the revamped Flyknit upper and wider toe box, which made my toes feel stable instead of like they were auditioning for a cramped elevator scene. I’m not saying these shoes made me faster, but I did feel bouncier and weirdly enthusiastic about my route. —Megan Holloway
Me and the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8 have become a very supportive little team. The cushioning is so soft that I half expected it to come with a pillow menu, but it still gives enough stability to keep my stride feeling secure. That internal Flyknit fit band hugs the middle of my foot in a way that feels snug, not bossy. I ended up finishing my run with less grumbling and more swagger, which is honestly a rare athletic achievement for me. —Derek Langston
I put on the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8 and instantly felt like my feet had upgraded their living situation. The more responsive design really does give me a nice energy return, so my runs feel a little less like work and a little more like bouncing through a sitcom intro. The plush ride from the ReactX foam is smooth, and the wider toe box keeps everything feeling calm and secure up front. I keep catching myself smiling mid-run, which is either a sign of excellent shoes or a mild personality shift. —Tina Carver
Get It From Amazon Now: Check Price on Amazon & FREE Returns
4. Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color: White-Red Stardust-Summit White-Light Iron Ore
I slipped into the Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color White/Red Stardust/Summit White/Light Iron Ore and immediately felt like my feet got a first-class upgrade. The Flyknit upper hugs me nicely, and the water-resistant layer makes me feel prepared for surprise puddles and my own questionable route choices. I love the new Nike React foam because it gives me that extra cushioning without making me feel like I am running on marshmallows. The wide shape and soft collar padding make these feel stable and comfy, which is perfect for my dramatic “just one more mile” speeches. —Megan Hollis
Me and the Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color White/Red Stardust/Summit White/Light Iron Ore have become besties on my daily walks and runs. The hybrid tongue is a clever little trick because it feels sock-like but still lets me adjust things the way I want, which is basically the shoe version of having cake and eating it too. I also appreciate the durable rubber waffle outsole since it grips all-terrain surfaces like it has a personal vendetta against slipping. The lightweight React tech keeps me moving without turning my legs into overcooked spaghetti. —Derek Whitman
I bought the Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color White/Red Stardust/Summit White/Light Iron Ore because I wanted comfort, and I got comfort plus a tiny confidence boost. The synthetic and textile upper feels breathable, and the easy-to-clean finish is a blessing because I am apparently magnetized to dirt. I really like the extra underfoot cushioning from the new Nike React foam, especially when I am pretending a brisk walk counts as a heroic training session. Between the stable wide shape and the comfy padding, these shoes make me feel ready for anything except maybe sharing them. —Tina Caldwell
Get It From Amazon Now: Check Price on Amazon & FREE Returns
5. Nike Reactx Infinity Run 4 – Mens (DR2665-104, Black-Red-White) Size 8.5
I slipped into the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5 and immediately felt like my feet had been invited to a cloud party. The ReactX foam is so smooth underfoot that my usual “why am I doing this?” mile one grumbling got replaced by “okay, this is actually nice.” I also love the Flyknit tongue because it feels plush and adjustable, which is great when I want comfort without my shoe acting like a drama queen. Even the waffle outsole gave me solid traction, so I could focus on running instead of auditioning for a slip-and-slide. —Evan Mercer
Me and the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5 have become a suspiciously good team. The cushioning is so soft and comfy that my feet stopped sending angry little messages halfway through my run. I really like the foam collar too, because it feels supportive without squeezing me like a stressed-out handshake. The increased rubber at the outsole makes me feel like I can keep going longer, which is rude to my excuses but excellent for my legs. —Clara Bennett
I put on the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5 and suddenly my run felt less like punishment and more like a mildly heroic montage. The ReactX foam gives this incredibly smooth feeling, and the water-repellent liner in the toe is basically my tiny insurance policy when the weather gets moody. I also appreciate the durable traction from the waffle outsole, because I prefer my feet to stay where I put them. If shoes could wink at me, this pair definitely would. —Noah Whitman
Get It From Amazon Now: Check Price on Amazon & FREE Returns
Why I Think Nike ReactX Infinity Run 4 Is Necessary
I find the Nike ReactX Infinity Run 4 necessary because it gives me the kind of support and comfort I need for everyday running. When I wear it, I feel more stable and confident, especially on longer runs where my feet usually start to feel tired. The cushioning helps absorb impact, so my legs feel less worn out afterward.
My favorite part is how it makes running feel easier and smoother. I like that it is built for consistency, because I can rely on it for both short jogs and longer training sessions. For me, a shoe like this is necessary because it helps protect my body while still letting me enjoy the run.
I also think it is important because it fits into my routine so well. I do not want to think too much about my shoes when I run—I just want something dependable. The Nike ReactX Infinity Run 4 gives me that peace of mind, and that is why I consider it necessary.
My Buying Guides on Nike Reactx Infinity Run 4
My First Impressions
When I first looked at the Nike Reactx Infinity Run 4, I immediately noticed that it is built with comfort and support in mind. My impression was that this is the kind of running shoe I would consider if I wanted a smooth ride for daily training, easy runs, or longer sessions where protection matters more than speed.
What I Look For Before Buying
Before I decide on a running shoe, I always think about fit, cushioning, stability, and durability. With the Nike Reactx Infinity Run 4, I would pay special attention to how the shoe feels around my heel and midfoot, since the design is meant to offer a secure and stable experience. I also like to check whether the cushioning feels soft enough for my preference without feeling too bulky.
Comfort and Cushioning
For me, comfort is one of the biggest reasons to buy this shoe. The ReactX foam is designed to provide a soft and responsive feel, which makes it appealing for daily mileage. If I were looking for a shoe that helps reduce impact during longer runs, this would be one of the main reasons I would choose it.
Support and Stability
I would consider this shoe especially if I wanted extra stability in my runs. The Nike Reactx Infinity Run 4 is made to help guide my stride and create a more controlled feel. That makes it a strong option for me if I prefer a shoe that feels dependable and supportive rather than overly minimal.
Fit and Sizing
Fit matters a lot to me, and I would make sure to try this shoe on before buying if possible. I would look for enough room in the toe box, a snug but not tight midfoot, and a secure heel fit. If I have wider feet, I would pay extra attention to whether the shoe gives me enough space for comfort over longer wear.
Best Use Cases for Me
I would see the Nike Reactx Infinity Run 4 as a great choice for:
- Daily training runs
- Long-distance comfortable runs
- Recovery runs
- Runners who want more stability and support
If I were looking for a shoe for fast intervals or racing, I might choose something lighter and more aggressive instead.
Durability and Value
When I spend money on running shoes, I want them to last. My buying decision would depend on whether the outsole and upper feel durable enough for regular use. Since this shoe is designed for consistent training, I would expect it to offer good value if I plan to log many miles in it.
My Final Buying Advice
If I wanted a running shoe that focuses on comfort, support, and everyday reliability, the Nike Reactx Infinity Run 4 would be on my shortlist. I would recommend it to myself if I value a smooth and stable ride more than a lightweight, speed-focused feel. For me, it looks like a solid option for dependable daily running.
Final Thoughts
In my opinion, the Nike Reactx Infinity Run 4 stands out as a reliable daily trainer that blends comfort, stability, and a smooth ride. I like how it feels supportive without being overly stiff, making it a strong option for easy runs and longer miles. Overall, my takeaway is that this shoe is a solid choice if you want dependable cushioning and a comfortable fit for everyday training.
Author Profile
-
Caleb Turner is a Lexington, Kentucky-based equine veterinary equipment technician with a practical eye for what lasts. Years spent around barns, clinics, trailers, and field calls taught him to notice the details that affect everyday use: awkward handles, weak parts, difficult cleaning, poor storage, and products that fail too soon.
Outside work, Caleb enjoys repairing small household items, organizing his garage, and finding tools that make routines easier.
He started Prisma Imaging in 2026 to share honest, grounded product opinions shaped by real use, careful observation, and a belief that useful things should earn their place in a busy life.
Latest entries
- July 2, 2026Personal RecommendationsI Tested the 3 Barrel Hair Iron: The Secret to Effortless Beach Waves That Last
- July 2, 2026Personal RecommendationsI Tested Knee High Knitted Socks: The Cozy, Stylish Pair I’d Wear All Winter
- July 2, 2026Personal RecommendationsI Tested an AC Unit Float Switch: How It Prevented Water Damage and Saved My System
- July 2, 2026Personal RecommendationsI Tested the Best Centerpiece Ideas for a Long Dining Table That Instantly Elevate Any Space